Monkeypox virus-induced upregulation of interleukin-10 signaling: could epigenetics be involved in long-term viral persistence?Editorial Published on 2023-04-012023-06-09 Journal: Hospital practice (1995) [Category] 원숭이두창, [키워드] epigenetics interleukin-10 Monkeypox virus persistence. [DOI] 10.1080/21548331.2023.2179770 PMC 바로가기 [Article Type] Editorial
Screening of an epigenetic compound library identifies BRD4 as a potential antiviral target for hepatitis B virus covalently closed circular DNA transcriptionArticle Published on 2023-03-012023-06-13 Journal: Antiviral Research [Category] B형 간염, [키워드] BRD4 cccDNA. epigenetics HBV [DOI] 10.1016/j.antiviral.2023.105552 PMC 바로가기
Involvement of epigenetics in affecting host immunity during SARS-CoV-2 infectionReview Published on 2023-03-012023-07-11 Journal: Biochimica et biophysica acta. Molecular basis of [Category] COVID19(2023년), [키워드] COVID-19 epigenetics Human immune responses severe acute respiratory syndrome coronavirus-2. [DOI] 10.1016/j.bbadis.2022.166634 PMC 바로가기 [Article Type] Review
Epigenetic perspectives of COVID-19: Virus infection to disease progression and therapeutic controlResearch article Published on 2022-12-012022-10-05 Journal: Biochimica et biophysica acta. Molecular basis of [Category] COVID19(2023년), SARS, 변종, 신약개발, 유전자 메커니즘, 치료제, [키워드] ACE2 analysed antagonistic autophagy caused Cell cellular metabolism cellular processe Course COVID-19 death Disease progression enzyme Epigenetic epigenetics example expression profile function genes encoding Genome Host host cell IL-6 Infection investigated Laboratory Lipid mechanism membrane metabolic activity metabolic pathway methionine pathogen invasion patients Perspective progression rDNA Regulation replication mechanism ribosome S-adenosylmethionine SARS-CoV-2 sera social isolation the disease the patient therapeutic therapy tissue viral loads virus virus particle virus replication [DOI] 10.1016/j.bbadis.2022.166527 [Article Type] Research article
Exhaustion and over-activation of immune cells in COVID-19: Challenges and therapeutic opportunitiesReview Published on 2022-12-012023-07-10 Journal: Clinical immunology (Orlando, Fla.) [Category] COVID19(2023년), [키워드] COVID-19 epigenetics Exhaustion Immune inhibitory receptors immunomodulation SARS-CoV-2. [DOI] 10.1016/j.clim.2022.109177 PMC 바로가기 [Article Type] Review
Epigenetic regulation of Fructose-1,6-bisphosphatase 1 by host transcription factor Speckled 110 kDa during hepatitis B virus infectionArticle Published on 2022-11-012023-06-12 Journal: The Febs Journal [Category] B형 간염, [키워드] epigenetics Fructose-1,6-bisphosphatase gluconeogenesis Hepatitis B virus hepatocellular carcinoma. Speckled 110 kDa [DOI] 10.1111/febs.16544 PMC 바로가기
A Review: Highlighting the Links between Epigenetics, COVID-19 Infection, and Vitamin DArticle Published on 2022-10-142022-11-16 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Apoptosis changes in Chromatin structure contribute COVID-19 COVID-19 infections disease risk drug Effect Epigenetic epigenetic modification epigenetics Evidence Gene Expression Health help highlight Host immune response Immunity immunomodulatory effect indicate individual Infection Inflammation involved mechanisms Modification modulated multifunctional outcomes pathophysiology Prevent proliferation receptor receptor function reduced regulate SARS-CoV-2 target therapeutic therapeutic drug Treatment Vaccine viral outbreak virus Vitamin D vitamin D. while [DOI] 10.3390/ijms232012292 PMC 바로가기
Epigenetic mechanisms and host factors impact ACE2 gene expression: Implications in COVID-19 susceptibilityResearch article Published on 2022-10-012022-10-05 Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ACE2 gene ACE2 protein age angiotensin-converting enzyme 2 Arterial hypertension association Asthma BMI body mass index changes in clinical variable clinical variables COVID-19 COVID-19 susceptibility described determinant disease susceptibility DNA methylation Epigenetic epigenetics evaluate evaluated expression expression profile Factor Host host cell host factors Infection involved Male sex mechanism Methylation molecular cause mRNA expression nasopharyngeal swab sample obesity overexpression Peripheral blood promoter region quantified regulated Result risk factor RT-qPCR SARS-CoV-2 SARS-COV-2 infection Sex significant difference smoking study group susceptibility the disease type II diabete underlying disease Variability variable virus volunteers was determined [DOI] 10.1016/j.meegid.2022.105357 [Article Type] Research article
SARS-CoV-2 mimics a host protein to bypass defencesComment Published on 2022-10-012023-07-10 Journal: Nature [Category] COVID19(2023년), [키워드] epigenetics SARS-CoV-2. [DOI] 10.1038/d41586-022-02930-2 PMC 바로가기 [Article Type] Comment
Impaired activation of transposable elements in SARS-CoV-2 infectionArticle Published on 2022-09-052022-11-15 Journal: EMBO Reports [Category] SARS, 유전자 메커니즘, 치료제, [키워드] activate activated Activation Cell cellular changes in Chromatin structure correlation COVID-19 Defense drug target element elements Epigenetic epigenetics Evidence explain expression expression level functional Genes Host host immune system identify immune Impaired Infection interferon interferon response mechanism primary cells Proteins provide regulate robust SARS-CoV-2 SARS-COV-2 infection suggested the SARS-CoV-2 Transcription transposable elements. upregulation variable viral infections Viral load viruses [DOI] 10.15252/embr.202255101 PMC 바로가기